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Wednesday, August 5, 2020 | History

2 edition of Urinary dolichols as biological markers of alcoholism found in the catalog.

Urinary dolichols as biological markers of alcoholism

Risto Roine

Urinary dolichols as biological markers of alcoholism

by Risto Roine

  • 310 Want to read
  • 5 Currently reading

Published by [s.n.] in Helsinki .
Written in English

  • Alcohol -- Physiological effect.,
  • Biochemical markers.

  • Edition Notes

    Statementby Risto Roine.
    ContributionsHelsingen yliopesto. Research Unit of Alcohol Diseases., Alko Oy. Research Laboratories.
    LC ClassificationsQP"801"A3"R65"1988
    The Physical Object
    Pagination56 p. :
    Number of Pages56
    ID Numbers
    Open LibraryOL20709978M
    ISBN 109518913137

    Alcohol intake may provoke urinary retention in young persons without a previous history of obstructive urinary tract disease. The mechanism by which alcohol causes urinary retention is unknown. Ten healthy male volunteers had urodynamic studies performed before and under the influence of alcohol. COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

      Free Online Library: Scand J Clin Lab Invest.: Biomarkers of alcoholism: an updated review.(Abstract, Report) by "Journal of Continuing Education Topics & Issues"; Alcoholism Diagnosis Biological markers Research Blood Medical examination Methods Blood tests Metabolites Health aspects Properties Transferrin Identification and classification. This article presents an overview of the current literature on biological markers for alcoholism, including mark-ers associated with the pharmacological effects of alcohol and markers related to the clinical course and treatment of alcohol-related problems. Many of these studies are well known, while other studies cited are new and still being.

    The search for biochemical markers for the objective diagnosis of alcoholism has been a topic of research because of the important clinical and forensic implications. In the last few years, two minor ethanol metabolites (ethylglucuronide and fatty acid ethyl esters) have been mainly investigated in hair samples for their ability to be. †† Biological activity of oz cranberry juice cocktail. ††† The Pharmacy Times Survey (Urinary Pain Relief and Cranberry Supplements). †††† Howell, A. , Bacterial Anti-adhesion Activity of Human Urine Following 27% Cranberry Juice Cocktail vs. PACran ® Capsule Consumption.

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Urinary dolichols as biological markers of alcoholism by Risto Roine Download PDF EPUB FB2

Correlations between EER and self–reported alcohol consumption have been found, as have correlations between EER and several other markers of alcohol abuse.

Sensitivity and specificity values for this potential marker in detecting alcohol consumption > 50 g/d have been reported as 88 percent and 92 percent, respectively (Olsen et al. There are several other markers with considerable potential for more accurate reflection of recent alcohol intake.

These include carbohydrate deficient transferrin, β-hexosaminidase, acetaldehyde adducts and the urinary ratio of serotonin metabolites, 5-hydroxytryptophol and 5 Cited by: Aubin HJ, Laureaux C, Zerah F, Tilikete S, Vernier F, Vallat B, Barrucand D () Joint influence of alcohol, tobacco, and coffee on biological markers of heavy drinking in alcoholics.

Biol Psychiatry – PubMed CrossRef Google ScholarCited by: M. Salaspuro, U. Korri, H. Nuutinen, and R. Roine () Blood acetate and urinary dolichols-new markers of heavy drinking and alcoholism, in Genetics and Alcoholism. Int. Titisee Symposium, Liss, New York, pp. – Google ScholarCited by: 1.

Download Citation | Biological markers in alcoholism | Alcohol biomarkers include tests indicative of acute or chronic alcohol consumption (state markers), and markers of a genetic predisposition Author: Anders Helander.

Thus, it has been proposed that urinary dolichols could be used as biological markers of alcoholism [14]. However, before this is possible, the effect of abstinence after an alcoholic bout and the effect of mod- erate drinking on urinary dolichols have to be established.

The aim of this study was to clarify these two aspects. A study of urinary dolichols as a biological marker for alcohol abuse. Report 1: Quantitation of urinary dolichols by high performance liquid chromatography after BondElutC18 ( mg) cartridge extraction.

Kazunaga H, Suwaki H, Fuke C, Ameno K, Ijiri I. Arukoru Kenkyuto Yakubutsu Ison, 29(3), 01 Jun Alcoholism causes changes to the brain in at least four fundamental ways: 1. Alcoholism causes changes to the brain's natural balance (homeostasis).

Alcoholism alters brain chemistry. Alcoholism changes the brain's communication patterns. Alcoholism causes changes to brain structures and their functioning.

Metabolites of alcohol indicate a level of alcohol consumption associated with biological changes in the body and may be used as markers.

Alcohol Metabolism and Products. Alcohol circulating in the blood reaches the liver, placenta, and other metabolic organs of both the mother and the fetus, where it can be broken down or conjugated to other. The demonstrated role of genetics in increasing the risk of alcoholism has promoted the search for biological markers that could objectively identify individuals who are genetically predisposed to alcoholism.

Identifying such markers could allow for early diagnosis, focused prevention, and differential and type-specific treatment of alcoholism. A study of urinary dolichols as a biological marker for alcohol abuse.

Report 1: Quantitation of urinary dolichols by high performance liquid chromatography after. A Kroke, J Dierkes, in Comprehensive Handbook of Alcohol Related Pathology, Other Markers: Dolichol.

Dolichol (long-chain polyprenols containing an α-saturated isoprene unit) acts as glycosyl carrier lipids in the biosynthesis of N-linked glycoproteins.

Since alcohol dehydrogenase (ADH) oxidizes this compound, an influence of alcohol intake on catabolism of dolichols has been suggested. The urinary ratio of the serotonin metabolites, 5- Two recently proposed biochemical markers of alcoholism, namely, quantitation of plasma transferrin variant (Tf) and the ratio of plasma.

Article “A study of urinary dolichols as a biological marker for alcohol abuse report 2: Comparison of urinary dolichols/creatinine concentrations among non-drinkers, moderate-drinkers and heavy-drinkers” Detailed information of the J-GLOBAL is a service based on the concept of Linking, Expanding, and Sparking, linking science and technology information which hitherto stood alone to.

Urinary ethyl glucuronide and 5-hydroxytryptophol levels during repeated ethanol ingestion in healthy human subjects. Alcohol and Alcoholism. 38, III. Helander A and Dahl H.

Urinary tract infection: a risk factor for false-negative urinary ethyl glucuronide but not ethyl sulfate in the detection of recent alcohol consumption. Keywords:Alcohol, alcohol dependence, analytical methods, biological markers, ethanol metabolites, biochemical techniques.

Abstract:Background: Ethyl alcohol is the most popular legal drug, but its excessive consumption causes social problems.

Despite many public campaigns against alcohol use, car accidents, instances of aggressive behaviour. alcohol use include crashes and other alcohol-related injuries, domestic tension and violence, neglectofworkandfamily,andanimmenseburden ofcoststosociety,includingcostsassociatedwith police, courts, jails, and unemployment.

Alto-gether, the consequences of alcohol abuse and dependence are estimated to cost the nation Biological markers of alcoholism J.B. Whitfield Department of Clinical Biochemistry, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales,Australia Pages   * Urinary dolichols are chemicals found in high levels in urine excreted by alcoholics.

One study tracked the urinary dolichols among 16 infants who were small for gestational age (Wisniewski et al. Among 6 of the 16 infants born to mothers who were heavy drinkers, 2 had FAS and 4 had effects consistent with alcohol-related birth defects.

Identification of subgroups of alcoholics with consistent biological markers within that subgroup may well prove more fruitful than aiming for identification of a trait marker for alcoholism in general. It may well be that genotypic research will prove more fruitful in marker identification than phenotypic research (Foroud et al., ).

Indeed. A Urinary Marker of Alcohol Intake’ marker of alcohol intake to complement the self-reported bevels usually assessed in epidemiological investigations.

A number of biological markers of ethanol intake and abuse have been proposed and most involve the collection of a blood specimen (8). Recently, Tang (9) developed an assay that measures. As researchers seek new ways to treat addiction as well as ways to prevent it, they are also trying to determine why some people are more susceptible to addiction than others.

One such avenue of research involves the interactions of genetic and .absorbed absorption acetyl activity alcohol alkaline alkaline phosphatase amino acids analysis antibodies antigen aromatic assay atoms bilirubin binding biological monitoring biological monitoring markers body bonds breath calcium cancer carbon carcinogens cause chemical chloride cholesterol chronic clinical compounds concentration condoms.